Northstar True Direction | Addressing Biotech's Other Unmet Need

The Unmet Need

Build the Breakthrough. Not the Back Office.

Founders are often pulled into financial models, cap table management, investor updates, HR needs, and operational questions — work that matters, but work that can distract from the science creating the company's value. It's a structural problem. And it's exactly what Northstar was built to solve.

"The same way your drug addresses an unmet need for patients — Northstar addresses the unmet business need behind your breakthrough."

The Business Behind Your Breakthrough

A trusted partner covering the business functions that matter most — so you can stop managing the business and get back to advancing the science.

Areas of focus

→ Finance & Capital → Investor Relations → Operations → Strategy

What Northstar Does

The business behind the science,
handled.

Not a consultant. Not a part-time hire. A dedicated business partner with 20+ years inside biotech — senior leadership at the stage when it matters most.

◈

Finance

Financials investors trust and a capital story that compels. FP&A, cash management, accounting, controls, investor relations, and cap table planning — built around your milestones.

◈

Operations

Operations that run without pulling you in. HR, IT, vendor oversight, insurance, and tax filings handled — so leadership stays focused on the science.

◈

Strategy

A strategic partner at the leadership table. Business transformation, growth planning, and a trusted sounding board for the CEO.

Why Northstar

Addressing Biotech's
Other Unmet Need.

Northstar covers what early-stage founders need most — finance, operations, capital strategy, and organizational infrastructure under one trusted lens. Because the right business infrastructure doesn't just support your science — it protects runway, clarifies ownership decisions, and amplifies value to investors, partners, and the market. That's value creation.

Biotech-native expertise

Built inside pharmaceutical and life sciences — through IPOs, fundraises, and FDA milestones. Not a generalist who learned biotech from a brochure.

Breadth where it matters, depth where it counts

Finance, operations, and strategy under one trusted lens — eliminating the coordination gaps, duplicated costs, and blind spots that come from managing multiple vendors.

A partner, not a vendor

Northstar operates like a trusted member of your leadership team — fully committed to your mission, present in your decisions, and invested in your breakthrough.

Runway-conscious by design

Senior leadership depth without the full-time executive overhead — so your capital stays where it belongs: advancing the science and reaching the next milestone.

How We Engage

Structured around what your
company needs right now.

Every engagement is built around your stage, your goals, and your gaps — not a fixed model. Here's how most of our partnerships take shape.

Embedded

Ongoing

A dedicated partner working inside your leadership team — present in decisions, integrated across finance and operations, and fully committed to your mission for as long as you need it.

Project-Based

Defined Scope

A focused engagement built around a specific need — a fundraise, an audit readiness effort, an ERP implementation, or an operational buildout. Clear scope, clear outcome.

Retained Advisory

Strategic

Senior-level guidance on an ongoing basis — a trusted sounding board for capital strategy, investor relations, and organizational decisions as your company evolves.

The Approach

Finding your True North

Every engagement begins with listening — to the science, the team, the capital story, and the gaps no one has addressed. What follows is a true partnership built around your specific breakthrough and the infrastructure needed to get there.

Phase 01

Listen

The engagement begins with listening — to the science, the team, the financials, the capital structure, and the pressures you're navigating. A structured diagnostic of your full business landscape to understand exactly where you are, what's working, and what's standing between you and the next milestone.

Phase 02

Partner

Working alongside you — not for you — to define the operating model, priorities, and infrastructure the business needs. Every decision aligns to your science timeline, your capital needs, and your investors' expectations.

Phase 03

Execute

Hands-on leadership across the functions that need it most — building infrastructure, managing vendors, closing the books, and managing cash. The result: clean financials, a clear investor narrative, thoughtful capital planning, and an operational foundation that positions your company for growth and sets the stage for the next raise. That's value creation — not just back-office support.

Phase 04

Evolve

As your science advances, the business evolves with it — continuously refining operations, capital strategy, and infrastructure so the company is always positioned for the next stage: a financing, a milestone, a partnership, or an exit.

About

William Noss
CPA · CGMA
Founder, Northstar True Direction

With over 20 years of progressive finance and operations leadership in pharmaceutical and life sciences, Bill has navigated every stage of the biotech journey — from early-stage startup to global public company.

Bill has guided organizations through IPOs, non-dilutive financings, and significant capital raises across multiple pharmaceutical and life sciences companies. He has built finance and operations infrastructure from the ground up, implemented ERP systems, and developed the audit and compliance foundations that institutional investors and boards require.

The insight is simple: the founders who most need senior business leadership are rarely structured to have it. Bill founded Northstar True Direction to close that gap — so founders can focus entirely on the science. The name is personal: Northstar True Direction was named for his children, whose initials are N, T, and D. They are his true north. This company exists to help other founders find theirs.

"Great science creates value — but only when the business around it is built to articulate that value clearly. The right financials, the right investor story, and the right operational foundation don't just support the science. They accelerate it."

20+

Years in pharma & life sciences finance

ERP systems implemented

IPO

Executed & led to market

Companies built & scaled

Areas of expertise

Biotech Finance & Capital Markets
Cap Table & Dilution Management
FP&A & Cash Management
Investor Relations & Fundraising Strategy
Accounting, Controls & Audit Readiness
IPO Execution & SEC Reporting
Human Resources & People Operations
IT Oversight & ERP Implementation
Board Reporting & Governance
Business Transformation & Scaling

Build the Breakthrough. Not the Back Office.

The business behind the science,handled.

Addressing Biotech'sOther Unmet Need.